Bifidobacterium lactis BB-12®

Bifidobacterium lactis BB-12^®

“Bifidobacterium lactis, BB-12^® The most extensively studied strain of Bifidobacterium lactis.

Backed by 400+ published studies, including 225+ human clinical studies.

Soldier

Supports gut health, digestion, and bowel regularity.

Clinically evaluated for probiotic properties and human safety.

Found In

Dutchie Bio Duo Probiotics

Lactose Free Yogurt

Dutchie Bio Duo Probiotics Lactose Free

Lactose Free Drinking Yogurt

Dutchie Probiotic Yogurt 125g

Dutchie Probiotic Yogurt "Your Gut's Best Friend."

Health Benefits of

Bifidobacterium lactis BB-12^®

Digestive Health

Helps promote regular bowel movements in individuals with constipation.¹ Clinical study conducted in collaboration with Dutch Mill Co., Ltd.
Supports digestive health and bowel regularity in individuals with constipation.² Clinical study conducted in collaboration with Dutch Mill Co., Ltd.
Supports overall digestive health.³
Helps reduce the frequency and duration of diarrhea in infants.⁴
Helps relieve and reduce the duration of antibiotic associated diarrhea (AAD).⁵
Helps inhibit H. pylori and supports gut microbiome balance in individuals with H. pylori infection.⁶⁻⁷
Promotes the growth of beneficial gut bacteria.⁸

Immune Health

Enhances influenza specific antibody response.⁹
Helps reduce respiratory tract infections in infants.¹⁰⁻¹¹

Metabolic Health

Helps maintain healthy total and LDL cholesterol levels in individuals with type 2 diabetes.¹²

Brain & Nervous System

Supports cognitive function in middle aged and older adults.¹³

Internal Dutch Mill data on file. 
Saejong R et al. Effect of Fermented Milk Containing Probiotics on Constipation Symptoms and Immune System in Subjects with Constipation. Siriraj Med J. Vol. 64 No. 4 (2012): Jul-Aug. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/244170 
Eskesen D, et al. Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12^®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial. Br J Nutr. 2015;114(10):1638-46. https://pubmed.ncbi.nlm.nih.gov/26382580/ 
Chouraqui J P et al. Acidified milk formula supplemented with bifidobacterium lactis: impact on infant diarrhea in residential care settings. J Pediatr Gastroenterol Nutr. 2004 Mar;38(3):288-92. https://pubmed.ncbi.nlm.nih.gov/15076628/ 
de Vrese M et al. Probiotic bacteria stimulate virus-specific neutralizing antibodies following a booster polio vaccination. Eur J Nutr. 2005 Oct;44(7):406-13. https://pubmed.ncbi.nlm.nih.gov/15578195/ 
Wang, K Y et al. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori. Am J Clin Nutr. 2004 Sep;80(3):737-41. https://pubmed.ncbi.nlm.nih.gov/15321816/ 
Sheu BS et at. Pretreatment with Lactobacillus- and Bifidobacterium-containing yogurt can improve the efficacy of quadruple therapy in eradicating residual Helicobacter pylori infection after failed triple therapy. Am J Clin Nutr. 2006 Apr;83(4):864-9. https://pubmed.ncbi.nlm.nih.gov/16600940/ 
Savard P et al. Impact of Bifidobacterium animalis subsp. lactis BB-12 and, Lactobacillus acidophilus LA-5-containing yoghurt, on fecal bacterial counts of healthy adults. Int J Food Microbiol. 2011 Sep 1;149(1):50-7. https://pubmed.ncbi.nlm.nih.gov/21296446/ 
Rizzardini G, et al. Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12^® and Lactobacillus paracasei ssp. paracasei, L. casei 431^® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2012;107(6):876-84. https://pubmed.ncbi.nlm.nih.gov/21899798/ 
Rautava S, et al. Specific probiotics in reducing the risk of acute infections in infancy--a randomised, double-blind, placebo-controlled study. Br J Nutr. 2009;101(11):1722-6. https://pubmed.ncbi.nlm.nih.gov/18986600/ 
Taipale TJ, et al. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in infancy. Br J Nutr. 2011;105(3):409-16. https://pubmed.ncbi.nlm.nih.gov/20863419/ 
Ejtahed HS, et al. Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus. J Dairy Sci. 2011;94(7):3288-94. https://pubmed.ncbi.nlm.nih.gov/21700013/ 
Sanborn V et al. Randomized Clinical Trial Examining the Impact of Lactobacillus rhamnosus GG Probiotic Supplementation on Cognitive Functioning in Middle-aged and Older Adults. Neuropsychiatr Dis Treat. 2020 Nov 13:16:2765-2777. https://pubmed.ncbi.nlm.nih.gov/33223831/

Internal Dutch Mill data on file. 
Saejong R et al. Effect of Fermented Milk Containing Probiotics on Constipation Symptoms and Immune System in Subjects with Constipation. Siriraj Med J. Vol. 64 No. 4 (2012): Jul-Aug. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/244170 
Eskesen D, et al. Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12^®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial. Br J Nutr. 2015;114(10):1638-46. https://pubmed.ncbi.nlm.nih.gov/26382580/ 
Chouraqui J P et al. Acidified milk formula supplemented with bifidobacterium lactis: impact on infant diarrhea in residential care settings. J Pediatr Gastroenterol Nutr. 2004 Mar;38(3):288-92. https://pubmed.ncbi.nlm.nih.gov/15076628/ 
de Vrese M et al. Probiotic bacteria stimulate virus-specific neutralizing antibodies following a booster polio vaccination. Eur J Nutr. 2005 Oct;44(7):406-13. https://pubmed.ncbi.nlm.nih.gov/15578195/ 
Wang, K Y et al. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori. Am J Clin Nutr. 2004 Sep;80(3):737-41. https://pubmed.ncbi.nlm.nih.gov/15321816/ 
Sheu BS et at. Pretreatment with Lactobacillus- and Bifidobacterium-containing yogurt can improve the efficacy of quadruple therapy in eradicating residual Helicobacter pylori infection after failed triple therapy. Am J Clin Nutr. 2006 Apr;83(4):864-9. https://pubmed.ncbi.nlm.nih.gov/16600940/ 
Savard P et al. Impact of Bifidobacterium animalis subsp. lactis BB-12 and, Lactobacillus acidophilus LA-5-containing yoghurt, on fecal bacterial counts of healthy adults. Int J Food Microbiol. 2011 Sep 1;149(1):50-7. https://pubmed.ncbi.nlm.nih.gov/21296446/ 
Rizzardini G, et al. Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12^® and Lactobacillus paracasei ssp. paracasei, L. casei 431^® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2012;107(6):876-84. https://pubmed.ncbi.nlm.nih.gov/21899798/ 
Rautava S, et al. Specific probiotics in reducing the risk of acute infections in infancy--a randomised, double-blind, placebo-controlled study. Br J Nutr. 2009;101(11):1722-6. https://pubmed.ncbi.nlm.nih.gov/18986600/ 
Taipale TJ, et al. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in infancy. Br J Nutr. 2011;105(3):409-16. https://pubmed.ncbi.nlm.nih.gov/20863419/ 
Ejtahed HS, et al. Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus. J Dairy Sci. 2011;94(7):3288-94. https://pubmed.ncbi.nlm.nih.gov/21700013/ 
Sanborn V et al. Randomized Clinical Trial Examining the Impact of Lactobacillus rhamnosus GG Probiotic Supplementation on Cognitive Functioning in Middle-aged and Older Adults. Neuropsychiatr Dis Treat. 2020 Nov 13:16:2765-2777. https://pubmed.ncbi.nlm.nih.gov/33223831/

Bifidobacterium lactis BB-12^®