Lactobacillus paracasei Lpc-37
“Lpc-37 - Supports stress relief, emotional well being, and the Gut Brain Axis.”
Backed by 65+ published studies, including 47+ human clinical studies.
Therapist
Supports stress resilience, emotional well being, and the Gut Brain Axis.
Clinically evaluated for probiotic properties and human safety.
Health Benefits ofLactobacillus paracasei Lpc-37
Brain & Nervous System
- Supports emotional well being and a healthy stress response.¹⁻²
- Helps reduce stress and anxiety while supporting sleep quality.¹⁻²
Digestive Health
- Supports gut microbiome stability during and after antibiotic use.³⁻⁴
- Helps reduce the risk of antibiotic associated diarrhea.⁵⁻⁷
- Helps relieve infant colic.⁸⁻⁹
Immune Health
- Supports immune function, helps reduce the risk of illness, and promotes a healthy inflammatory response.¹⁰⁻¹²
Metabolic Health
- Supports fat and glucose metabolism in individuals at high risk of metabolic syndrome.¹³
- Patterson E et al. Lacticaseibacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical trial (the Sisu study). Neurobiol Stress. 2020. 13: 100277. https://pubmed.ncbi.nlm.nih.gov/33385020/
- Mäkelä S M et al. Efficacy and safety of Lacticaseibacillus paracasei Lpc-37® in students facing examination stress: A randomized, triple-blind, placebo-controlled clinical trial (the ChillEx study). Brain Behav Immun Health. 2023. 32: 100673. https://pubmed.ncbi.nlm.nih.gov/37662485/
- Engelbrektson F et al. Analysis of treatment effects on the microbial ecology of the human intestine. FEMS Microbiol Ecol. 2006. 57: 239-50. https://pubmed.ncbi.nlm.nih.gov/16867142/
- Engelbrektson F et al. Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy. J Med Microbiol. 2009. 58: 663-70. https://pubmed.ncbi.nlm.nih.gov/19369530/
- Ouwehand AC et al. Specific probiotics alleviate allergic rhinitis during the birch pollen season. World J Gastroenterol. 2009 Jul 14;15(26):3261-8. https://pubmed.ncbi.nlm.nih.gov/19598302/
- Barker A K et al. A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO). J Antimicrob Chemother. 2017. 72(11):3177-80. https://pubmed.ncbi.nlm.nih.gov/28961980/
- De Wolfe T J et al. Oral probiotic combination of Lactobacillus and Bifidobacterium alters the gastrointestinal microbiota during antibiotic treatment for Clostridium difficile infection. PLoS ONE 13(9): e0204253. https://pubmed.ncbi.nlm.nih.gov/30265691/
- Piatek J et al. Effects of a nine-strain bacterial synbiotic compared to simethicone in colicky babies - an open-label randomised study. Benef Microbes. 2021. 12(3): 249-57.https://pubmed.ncbi.nlm.nih.gov/33765904/
- Bernatek M et al. Nine-strain bacterial synbiotic improves crying and lowers fecal calprotectin in colicky babies – an open-label randomized study. Microorganisms. 2022. 10(2): 430. https://pubmed.ncbi.nlm.nih.gov/35208884/
- Paineau D et al. Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. FEMS Immunol Med Microbiol. 2208. 53: 107-13. https://pubmed.ncbi.nlm.nih.gov/18422632/
- Forssten S D et al. Influence of a probiotic milk drink, containing Lactobacillus paracasei Lpc-37, on immune function and gut microbiota in elderly subjects. Eur J Food Res. 2011. Rev 1: 159-72. https://journalejnfs.com/index.php/EJNFS/article/view/254
- Tingö L et al. Potential modulation of inflammation by probiotic and omega-3 supplementation in elderly with chronic low-grade inflammation – A randomized, placebo-controlled trial. Nutrients. 2022. 14(19): 3998. https://pubmed.ncbi.nlm.nih.gov/36235651/
- Yu P et el. Effect of an oral probiotic formula on scalp and facial skin condition, glucose, and lipid metabolism. Funct FoodsHealth Dis.2022. 12(7): 394-409. https://www.ffhdj.com/index.php/ffhd/article/view/944
